SLUH (2-0) at DeSmet (1-1), Friday, 6 p.m. — The two Metro Catholic Conference rivals meet in their league opener. Both are coming off impressive non-conference victories last weekend. SLUH defeated Hillsboro 35-0 while DeSmet defeated MICDS 31-14. Senior quarterback Gabe Rodriguez has passed for 500 yards and three touchdowns in his first year as a starter at DeSmet. Cam Sharp has rushed for 250 yards and two touchdowns. Kyren Eleby of SLUH has thrown for 390 yards and four touchdowns while senior Jordan Taylor has rushed for 253 yards.
East St. Louis (0-1) at Bishop Gorman (2-0), Friday, 9 p.m. — The Flyers continue their ambitious national schedule with a trip to Las Vegas to take on perennial national power Bishop Gorman. East Side was idle last weekend after having their game against Gadsden County canceled at the Gateway Scholars Classic. Bishop Gorman is 3-0 and ranked No. 3 in the latest Max Preps national football poll.
CBC (2-0) at Chaminade (2-0), Friday, 6 p.m. — Another Metro Catholic Conference matchup between two teams that are undefeated after two weeks. The Cadets posted an impressive 34-12 victory over Cardinal Ritter last week. They are led by exciting dual-threat quarterback Nick McClellan, who passed for a touchdown and ran for another against Cardinal Ritter. Chaminade has posted victories over McCluer North and Poplar Bluff.
Lafayette (2-0) at Kirkwood (2-0), Friday, 7 p.m. — This is an early season showdown between two teams that advanced to the state semifinals last season. Lafayette was in the Class 5 semifinals but has been moved up to Class 6. Kirkwood has been moved down to Class 5 after advancing to the Class 6 state semifinals last season. Lafayette has outscored its two opponents 94-0 in its two victories. Quarterback Brady Micek has passed for 368 yards and three touchdowns. Kirkwood features Illinois recruit Jacob Eberhart, who has 208 yards receiving and two touchdowns.
Lift for Life (2-0) at Baylor (2-0), Friday, 7 p.m. — Lift for Life will make the trip to Chattanooga, Tennessee to take on one of the top teams in the Volunteer State. The Hawks have opened the season with a pair of impressive road victories over MICDS and Cahokia. Baylor features multiple major college prospects, including five-star senior offensive tackle Gabriel Osenda and four-star junior running back David Gabriel Georges.