Troy Glaus hit a grand slam and the St. Louis Cardinals rocked Daisuke Matsuzaka in his return from the disabled list, beating the Boston Red Sox 9-3 Saturday.
On the DL since May 30 because of a mild strain in his rotator cuff, Matsuzaka (8-1) was tagged for seven runs in one-plus inning. It was shortest outing of his brief major league career.
Mitchell Boggs (2-0) pitched effectively into the sixth inning in his third big league start. Aaron Miles and Rick Ankiel also homered for St. Louis.
The Cardinals had scored just four runs in their previous three games before defeating Boston 5-4 Friday night.
The Red Sox are assured of dropping a series at Fenway Park for the first time since late April. They had won their previous seven series at home, their longest stretch since taking nine straight from July 18-Sept 8, 2005.
Given a big lead from the start, Boggs (2-0) gave up three runs and five hits in 5 1-3 innings.
Kyle McClellan, Russ Springer and Jason Isringhausen combined for 3 2-3 innings of one-hit relief.
Ankiel hit his 12th home run in the seventh.
Information from the Associated Press contributed to this report.