“font-size: 9.0pt; font-family: Verdana; mso-bidi-font-family:”>A

new study from researchers in Europe has drawn an association

between pregnant mothers’ sodium intake and their newborn’s kidney

development. Findings from researchers from the University of

Heidelberg and the University of Aarhus in Denmark, is published in

the online edition of the American Journal of Physiology –

Renal Physiology.

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“font-size: 9.0pt; font-family: Verdana; mso-bidi-font-family:”>According

to the study, either too much or too little salt during pregnancy

had an adverse effect on the prenatal development of the

offspring’s kidneys. The consequence of such disruption can lead to

high blood pressure in later years.

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“font-size: 9.0pt; font-family: Verdana; mso-bidi-font-family:”>Research

involved feeding mice low, medium and high sodium diets during

pregnancy and lactation, and then measuring blood pressure over

several weeks for male offspring and the amount of sodium and the

expression of proteins involved in kidney

development.

 

“font-size: 9.0pt; font-family: Verdana; mso-bidi-font-family:”>The

researchers found that the number of glomeruli (the main structural

unit of the kidney) during weeks 1-12 were significantly lower, and

the measured blood pressure for males after the fifth month was

higher in offspring of mothers on high- or low- compared with

intermediate-sodium diet.

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“font-size: 9.0pt; font-family: Verdana; mso-bidi-font-family:”>If

researchers can infer the findings in the animals in this study to

humans, both too low and too high salt intake during pregnancy

would be a risk factor for hypertension and renal damage in the

offspring.

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